Hair Improvement Protocol: Oral Minoxidil and Dutasteride+ Gel
Combination Protocol: Oral Minoxidil and Dutasteride+ Gel

Double down with
this custom combo

  • Combine two protocols for the best of both worlds
  • Oral Minoxidil is perfect for individuals who may have experienced irritation from topical treatment
  • Synergistic effects that compounds results beyond what each medication can do on their own
  • $79.99/mo, cancel anytime

Combination Protocol Ingredients

Dutasteride

Dutasteride

0.1%

What is it?

An off-label medication that acts as a 5AR inhibitor.

How does it work? 1

Targeted inhibition of dihydrotestosterone (DHT) at the scalp, minimizing systemic effects and enhancing hair regrowth.

Is it safe?

Side effects associated with Oral Dutasteride such as reduced libido and erectile disfunction are rare or absent when used in the topical format. See additional important safety information above.

Tretinoin

Tretinoin

0.01%

What is it?

A prescription retinoid commonly used in skincare applications.

How does it work? 2

It stimulates cell growth, increases blood supply to hair follicles, promotes collagen production, and reduces scalp inflammation. Tretinoin is shown to significantly improve growth results compared to using once-a-day topical medications on their own.

Is it safe?

Reported side effects are minimal, including itch or irritation. See additional important safety information above.

Minoxidil

Minoxidil

2.5mg

What is it?

A medication developed to treat blood pressure and frequently prescribed off-label for hair growth treatment

How does it work? 6

Promotes blood flow to hair follicles and potentially prolongs the hair’s growth (anagen) phase

Is it safe?

Low dose oral minoxidil is well-tolerated with no known severe cardiopulmonary events reported. See additional important safety information above.

Boosters

Boosters

0.0033%-0.1%

Fexofenadine 3

0.1%

Can reduce scalp inflammation which can contribute to hair loss

Melatonin 4

0.0033%

Shown to increase hair count up to 40% after 6 months of application

Caffeine

0.2%

Can enlarge hair follicles and promote growth

Combination: Oral Minoxidil and Dutasteride+ Gel

How this protocol stacks up

Each protocol is designed to deliver a customized approach to treatment. Whether you’re focused on targeted medication delivery, or maximum results, there is a perfect solution ready for you.

Need help deciding? Get started today and we’ll recommend your perfect protocol when you answer just two simple questions.

Systemic Impact
Targeted Delivery
Maximum Results
High
Medium
Low

Don’t forget the basics

Ensure your body has the nutrients it needs to battle hair loss and promote new growth. Our Building Blocks formulation is a doctor designed multi-vitamin that offers superior bioavailability compared to over the counter alternatives.

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power your body with nutrients

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Even the healthiest of diets are missing key vitamins and nutrients. Don’t settle for low quality store bought supplements- make sure you’re taking the best. Exclusively available only for Maximus protocol customers.

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How It Works

Easier than ever at-home treatment

Medical questionnaire

1. Product Finder

Use our product finder tool to pick your perfect protocol. Complete a brief medical questionnaire to capture your health needs and goals. A licensed doctor will review it and ensure you are a good candidate for this protocol.

Submit photos

2. Get Started

Medication will be delivered fast, free, and discretely. Be sure to take photos periodically to track your progress. These will be helpful to review with your doctor when completing a refill request.

Follow up & Optimization

3. Follow up & Optimization

Work with your doctor to perfect your protocol, ensuring you are progressing without any concerns. Keep in mind, hair regrowth requires consistency and most customers see results in 3-12 months.

Transparent Pricing

No hidden fees. Includes doctor consultations (+ unlimited messaging).

Hair Improvement Protocol

Price
Combination Protocol$79.99/month

Derma stamp device

Optional$14.99

Get Started

Unlimited Messaging

Unlimited Messaging
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Real customers, real results

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Before

After

Timothy F.

Verified buyer

Using: Maximus Hair Improvement Protocol

Before

After

Jacob B.

Verified buyer

Using: Maximus Hair Improvement Protocol

Before

After

Sakul N.

Verified buyer

Using: Maximus Hair Improvement Protocol

This isn’t your dad’s hair care

  • Fully customized protocols to meet your individual hair growth goals
  • A variety of oral, topical, and combination protocols that work with your lifestyle
  • Innovative ingredients that are designed to work together and get real results
  • No more office visits or pharmacy trips, discrete home delivery
Find Your Protocol

You have questions, we have answers.

Contact Support

Can I use the this protocol with other Maximus Protocols?

Yes. Many men experience the greatest improvements when on more than one Maximus protocol as they are complementary and hold no contraindications. Your dedicated Maximus doctor will review your total health goals and symptoms to ensure you achieve the optimal results whether you are on one or multiple protocols.

Can I use the Hair Improvement Protocol if I’ve had a hair transplant?

Please consult the doctor that performed the transplant to confirm when topicals may be safely applied. Disclose this information to your Maximus doctor.

What’s included in the cost?

Costs include your medical review, unlimited doctor messaging, shipping, and medication. Because hair products require at least a few months of use for visible results, we offer 3 month packages to ensure you have enough medication and time to properly get going on the protocol. If you are not a candidate for treatment, you'll be eligible for a refund, less $30 for the initial doctor's consultation. The dermastamp device is an optional add-on purchase ($14.99) and can be purchased alongside topical protocols.

How do I know if the hair medication is working?

As part of each refill you will have the opportunity to send new pictures of your hair growth, which will be shared with your doctor so that you can discuss results and track your progress over time.

What states is this protocol available in?

This product is currently available in all US States, including District of Columbia.

Can I use my HSA or FSA card to pay for The Hair Improvement Protocol?

Yes! Maximus accepts Health Savings Accounts (HSA) and Flexible Spending Accounts (FSA).

Using your HSA/FSA is easy. Simply use your HSA/FSA card as you would any other debit or credit card when providing your billing information.

HSA/FSA plans vary on what services they are willing to cover. If you are uncertain whether your plan covers Maximus' services, check with your plan administrator.

Are these products different from Maximus Warrior Protocol or the Latanoprost formula?

Yes, we are always working to offer the most safe and innovative products and have created larger portfolio of products that are both efficacious and affordable. If you are looking for a specific formulation (such as Latanoprost) or customization, please ask your doctor to see if it can be accommodated.

Does your topical gel contain propylene glycol?

Maximus minimizes use of propylene glycol to avoid the greasiness and risk of irritation of the scalp associated with it. Our standard gel product does not include propylene glycol. However there may be a chance that your doctor prescribes a different (non-gel) format, which may include propylene glycol, but at an extremely low concentration of 0.0045%.

Will the Hair Improvement Protocol gel make my hair look greasy once applied?

The Hair Improvement Protocol uses a dehydrated base to prevent giving the hair a greasy appearance once applied.

What if the topical solution causes scalp irritation?

Please discuss any side effects or irritation with your doctor, they will advise clear options or next steps to reduce irritation.

What if I miss a day of topical treatment?

Consistency is key, get back on track with application as directed by your doctor as soon as possible. If you find that you are struggling with the daily topical application, you can discuss oral medication options with your doctor as well.

What is the Derma Stamp and how do I order one?

Maximus sells a microneedle device called a Derma Stamp. It is recommended to be used in conjunction with any of the topical medications to improve absorption and stimulate follicle growth. Studies have shown that when you combine minoxidil (a key ingredient) with microneedling, you can boost hair growth by 4x. You’ll be able to add a dermastamp to your order at checkout for $14.99.

Does the Derma Stamp hurt?

The Derma Stamp uses very shallow needles and is applied with an even pressure, lightly into the skin. This can cause mild discomfort, including after treatment. But most customers report that it is very tolerable and easy to use.

What are the possible side effects of this protocol?

Topical Dutasteride+ Gel:
Due to decreased systemic absorption, side effects are less common than with oral dutasteride.
Common side effects include:
Mild scalp irritation.
Temporary hair shedding.
Rare but serious side effects (less likely than with oral dutasteride):
Allergic reactions such as rash or swelling.
Hormonal side effects such as decreased libido, breast tenderness, or changes in mood.

Oral Minoxidil:
Common side effects include:
Water retention or swelling in extremities.
Increased hair growth in unintended areas.
Serious side effects include:
Rapid heart rate.
Signs of fluid overload, such as shortness of breath.

Seek immediate medical care for any severe or concerning symptoms.


What else should I know about this protocol?

Avoid using other scalp treatments simultaneously without your provider's approval.
Follow-up visits may be needed to assess your response to treatment.
Avoid allowing others to come into contact with the treated area before it is dry.
Do not exceed the recommended dose or frequency of use.


1
Topical dutasteride is an effective treatment for androgenetic alopecia (AGA) due to its targeted inhibition of dihydrotestosterone (DHT) at the scalp, minimizing systemic effects and enhancing hair regrowth. The following findings support its use:

Reversal of Miniaturization: Studies show that topical dutasteride significantly increases hair shaft diameter and improves the terminal to vellus hair ratio, reversing the follicular miniaturization caused by DHT

Superior Potency: Dutasteride is more effective than finasteride at inhibiting both Type I and Type II 5 alpha reductase enzymes, making it a potent option for addressing androgen driven hair loss

Localized Action and Safety: Topical dutasteride limits systemic absorption, as evidenced by unchanged serum DHT and testosterone levels, reducing the risk of sexual or hormonal side effects commonly associated with oral formulations

Patient Reported Improvements: Clinical trials report higher patient satisfaction with hair density, appearance, and slowing of hair loss with topical dutasteride compared to other therapies.
2
Topical tretinoin enhances the response to minoxidil in individ uals with low follicular sulfotransferase activity, the enzyme required for converting minoxidil into its active form. Increased sulfotransferase activity following tretinoin application resulted in 43% of initial nonresponders becoming responders. Tretinoin allows for once daily minoxidil application. Twice a day application of minoxidil yields better results without tretinoin

The addition of tretinoin to minoxidil therapy does not increase the incidence of adverse effects compared to minoxidil alone. Reported side effects, such as pruritus or local irritation, occurred at similar rates in both treatments
3
Fexofenadine, a second generation antihistamine, reduces inflammation through its H1 receptor antagonism, potentially mitigating inflammatory responses implicated alopecia. Chronic scalp inflammation contributes to hair follicle miniaturization in various forms of alopecia, and fexofenadine’s ability to suppress histamine driven inflammation may help
address this underlying factor.
4
Melatonin, most known for its role in mediating the wake sleep cycle, has actually been shown to increase the hair count 40% after six months of application.
5
Microneedling (with minoxidil) increases mean hair count 4.1x compared to minoxidil alone.
6
Safety: Low-dose oral minoxidil (OM) is well-tolerated, with the most common side effect being hypertrichosis (excessive hair growth), which was reported in about 20% of patients and typically mild and manageable. Cardiovascular side effects, such as minor blood pressure changes or edema, were rare and dose-dependent, primarily occurring at higher doses. No severe cardiopulmonary events were reported, highlighting the overall safety of low-dose OM

Efficacy: OM effectively increases hair density, hair thickness, and the proportion of hairs in the anagen (growth) phase. Studies show significant improvements in androgenetic alopecia (AGA) outcomes in both men and women, with doses ranging from 0.25 mg to 5 mg daily providing notable results. OM has also demonstrated efficacy in patients with conditions like telogen effluvium and other alopecia types

Comparison to Topical Minoxidil: OM offers comparable efficacy to topical 5% minoxidil, with some studies indicating better patient-reported outcomes and improved hair shedding scores. Unlike topical formulations, OM avoids issues like scalp irritation and low compliance due to its once-daily oral administration, making it a convenient alternative for patients who struggle with topical application

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The above and following information relates to studies of specific individual hair growth ingredients, some of which are used in the Hair Improvement Protocol. Please note, however, that while individual ingredients may have been shown to exhibit certain independent effects when used alone, the specific combination of ingredients contained in this product have not been tested in clinical trials. No specific claims are being made that use of this product will lead to the precise effects discussed above and below.